Maybe its just me. But I've got a problem with people who use the express lane like a cruise lane. If you want to go slow, use one of the other lanes. Just because you qualify for the express lane, doesn't mean you need Read more
The # symbol, called a hashtag, is used to mark keywords or topics in a Tweet. It was created by Twitter users as a way to categorize messages into subjects, so they can be easily searched. Now I get the simplicity of this, however, Read more
Ok, its rather technical, forgive me for "geeking" out on you, but I love Objective C, but I really think, the NSString object is overly complex. Some simple overrides (like those offered in C# with the String Class) would be very helpful.
For those who Read more
I recently had a church lesson, of all things on the 12 Things Happy People Do Differently. I found it rather provocative, and extremely practical, so I thought Id echo the points here, and add my two cents. These are vitally true. I think Read more
Protandim Study #12 as we’re calling it, focuses on Protandim’s ability to reduce hypertension and what it can mean for human intervention in future studies. This is followup review from the previous VCU study published in the American Heart Association study, and adds:
Significance: Pathobiological mechanisms which contribute to pulmonary vasoconstriction, lung vascular remodeling and the development of right heart failure include the generation of reactive oxygen and nitrogen species and the response of lung vascular and cardiac cells to these molecules. We review the information regarding oxidant stress balanced by antioxidant mechanisms and the role of oxidants and antioxidants in hypoxic pulmonary hypertension and their potential role in an animal model of severe pulmonary arterial hypertension (PAH). Recent Advances: In human lung tissue from patients with idiopathic PAH we find reduced SOD activity and high expression of the oxidant stress markers nitrotyrosine and 8-OH-guanosine. In the Sugen 5416/chronic hypoxia model of PAH lung tissue expression of nitrotyrosine and hemeoxygenase 1 (HO-1) is substantial, while HO-1 expression in the failing right ventricle is decreased. This model, based on administration of the VEGF receptor blocker Sugen 5416 and chronic hypoxia (Su/Hx), reproduces many of the characteristic features of severe angioobliterative human PAH. Treatment of Su/Hx rats with ‘protandim,’ which Nrf-2-dependently upregulates the expression of genes encoding antioxidant enzymes, protects against right heart failure without affecting angioobliterative PAH. Critical Issues: In human severe PAH, patient survival is determined by the function of the stressed right ventricle; investigation of oxidative and nitrosative stresses and their potential contribution to right heart failure is necessary. Future Directions: Antioxidant therapeutic strategies may be of benefit in the setting of human severe PAH. Whether antioxidant strategies affect lung vascular remodeling and/or prevent right heart failure remains to be examined.
A new Protandim study conducted by the Department of Health and Exercise Science, Colorado State University, shows that Protandim when used in vitro with human cells that line the inside of coronary arteries are dramatically protected from cellular death caused by oxidative stress. The study shows that without Protandim 34% of cells “die” however when pretreatment with Protandim resulted in only 6% cell death. This study shows Protandim stimulates via Nrf2 the production of several key proteins and enzymes (in some cases twice as much or up to 7 times as much more) that fight free radical damage. This study shows Protandim can reduce endothelial cell oxidative stress and has potential to reduce associated vascular disease states.
In resarch released some years ago, Serum levels of TBARS were strongly predictive of cardiovascular events in patients with stable CAD, independently of traditional risk factors and inflammatory markers. See: http://www.ncbi.nlm.nih.gov/pubmed/15542282
This means that Protandim proven to reduce TBARS, could be a very strong preventative measure against heart disease. This echo’s findings from the American Heart Association’s published article on Protandim back in 2009.
Is TBARS a valid measurement of oxidative stress? Yes. And it speaks volumes to the clinical effects of what Protandim can do.
LifeVantage opened in Canada for customers in Sept 2011. Canadian is not open for distributors at this time, however the official annoucement for this is extremely close (see below for details). The cost of Protandim for customers in Canada is the wholesale price of $40 per bottle plus tax and shipping. I’ve found the best way (and the most affordable way) to buy Protandim for Canadians is on a quarterly basis (for example 3 bottles every 3 months), this saves you $17 or so dollars every 2 months, because shipping is currently expensive. Each bottle has 30 caplets, most people need only 1 pill per day so 1 bottle lasts one month per person.
Because LifeVantage is a referral based business, if you are already working with a LifeVantage distributor from the United States please place your order with them. If you do not have a distributor to help you order Protandim or if you need more information about how you can become involved in Canada, I’m happy to help you, contact me or use the links on this page.
Preferred customers qualify to earn rebates in Canada. This means you can refer other customers and receive a 25% rebate for each (up to a $120 credit). The only exception to the quarterly shipment recommendation above is if you have referrals. Referral rebates for customers are only given to preferred customers who are on a monthly autoship (not quarterly).
Normally, it takes about 8 business days after you order to receive an Protandim for preferred custom orders. Preferred c ustomers receive their orders in about 6 business days. You can also order TrueScience as well, which is an amazing product, and contains the ingredients of Protandim in a topical creme. Our Canine Health product is not available in Canada yet, until we receive government approval.
Being a distributor in Canada?
I’m in the process of working with existing customers and interested parties to upgrade or become distributors in Canada. I’m grouping these individuals based on geography and leadership interests. If you are interested in becoming a distributor in LifeVantage when Canada opens in the next several weeks (now estimating April or May 2013), please send me a message via email. Again, if you are currently working with an existing distributor from the United States, please continue to work with that person, however, I’m willing to answer any questions for anybody if I can be helpful.
There are two methods to buy Protandim now for Canada. One is become a preferred customer, the other is to place a one time order.
Option 1 – Preferred Customer Account
To create a preferred customer account there are no additional costs, you simply buy Protandim at $40 per bottle plus tax and shipping. Here is a short video on how to do that. Then send me an email, and if you prefer I will have LifeVantage change your order to quarterly or every other month. This saves you on shipping costs, however you will pay sales tax for your province or territory.
Watch this video about how to become a preferred customer below:
Option 2 – Custom Orders via Email or Phone
Call me (or contact me via email) for a custom Protandim order, or can help get you started that works for you.
PHONE ORDERS simply call 866-460-9610, or send me a message via email. On Phone orders we can simply setup a one time order or a customer order as you see fit.
Is Protandim sold inside Canada?
No. You have to purchase it from an authorized distributor located in the United States. Canada is only open for customers only, and Protandim is not allowed to be sold in retail stores, now or ever.
How are we opening Canada?
LifeVantage has obtained approval from Health Canada and has received an Exemption Number (EN-182906) for Protandim. We’re have received approval from the Competition Bureau, so we’re in accord with the laws of Canada. These things have been completed as of Jan 2013. Individual regulation requirements must be met with all provinces and territories, and we’re waiting on just 1 or 2 of these to be returned to us, so we can open the entire country at once. However everything else is ready to go, and once we receive these certificates, an official announcement will be made.
Can I be a LifeVantage distributor now?
Not until Canada is open for distributors. LifeVantage is doing this right, both legally and ethically. Stay tuned, but this option will be open shortly.